Malignant Hyperthermia (MH) – A potentially lethal inherited disorder that can cause a severe reaction to certain anesthesia medicine. This condition can result in patients having hypoxemia, hypercapnia, tachycardia, muscular rigidity, acidosis, hyperkalemia, hyperthermia, and the overall inability to wake up after surgery.

Here are a few of the most common reason for the Malignant Hyperthermia Panel:  

  • Infections and statin therapy can contribute to this medical condition, as can stress.
  • Untreated malignant hyperthermia (MH) crisis although rare has about a 90% fatality rate.
  • MH is an extremely dangerous and high-risk condition requiring immediate action for survival.
  • Malignant Hyperthermia can be triggered incidentally in patients by potent anesthetics agents. For example, halothane, sevoflurane, and desflurane, and succinylcholine. This condition can be determined with our genetic anesthesia test panel.
  • Children under the age of 15 account for 50% of cases
  • Relatives of anyone who has had an episode, should be tested prior to surgery

Panels that are offered at Tesis Biosciences include: 

  • 8-Gene Next Generation Sequencing (NGS) Panel